Mycotherapy: the natural power of fungi

What is Mycotherapy?

Mycotherapy is therapy using the fungal kingdom; that is, mushrooms, as medicinal elements. This term was coined by Researchers at Hifas da Terra in 2006 and since then it has been used worldwide to refer to therapy with fungi (or fractions of them) for health, prevention and integrative therapeutic support in various pathologies.

Medicinal mushrooms are fascinating producers of substances with positive effects for humans. A single species of medicinal fungus can contain hundreds of bioactive substances.

Modern science has discovered various hypolipemic, immunomodulatory and antitumor activities in medicinal mushrooms.

In addition, other antioxidant, antiviral, antibacterial, antiparasitic, hepatoprotective and antidiabetic properties have also been discovered.

Over the past 30 years, thousands of scientific papers have been published and multiple trials support the clinical applications of its ingredients:

Lentinan and PSK are used in the treatment of cancer in Japan
Erinacines help rebuild neural tissue
Lentionin is a powerful antiseptic used in toothpastes
Triterpenes act as powerful anti-inflammatory drugs with cortisone-like effects

Mycotherapy focuses on medicinal fungi as an object for research and development of nutritional products in order to maintain and improve human and animal health.

Why mushrooms?

First, the fungi that make up the Fungi reign are fascinating organisms that have survived by evolving and adapting to new scenarios. There are an estimated 1.5 million species of fungi in the world, but we actually know only about 100. They are intelligent and efficient beings who have managed to maintain their communication network in order to fulfill their biological function, while preserving their essential biochemical traits.

Then we need them to interconnect soil, nutrients and plants; a fundamental trinoma for the development of life on Earth, as well as the antibiotic discovery of one of them, Penicillum, which gave rise to penicillin.

In the Treatise on Medicinal Herbs Pen Tsao, one of the fathers of Chinese medicine, the famous Shen Nong, speaks of Reishi as a divine fungus capable of prolonging life and harmonizing physical and spiritual balance.

In the Bencao gangmu (Chinese Medicine Collection) of the doctor Li Shi Zhen (1518-1593), reishi is also referred to: “consumed over a long period of time, bodily agility will not cease and the years will continue like those of immortal beings“.

Our ancestors appropriated mushrooms and their applications.

Finally, mushrooms contain more than 150 bioactive compounds in their structure. Their consumption provides us with the best of bioavailable alpha and glucans, but also enzymes, prebiotics, natural antibiotics, B vitamins, ergostrerol, minerals such as selenium and zinc, essential amino acids and other nutrients that help homeostasis and/or body balance.

What can mushrooms bring us? (Some examples)

Shiitake (Lentinula edodes)

For starters, Shiitake has antitumor properties due to immuno-stimulating activity, which is protective of tumor development.
Lentinane stimulates the proliferation of T cells in the presence of interleukin-2, stimulates macrophage activity and interleukin-1 production.
There has been a marked decrease in the adverse effects of antitumor drugs.

It inhibits the adhesion and formation of bacterial biofilm by improving dental plaque. It is also a gastroprotector and an anti-oxidant.

It is usually used in an adjuvant combination with cancer chemotherapy.

Maitake (Grifola frondosa):

Maitake is an adaptogen and immunostimulant, it has arguably the strongest immune system stimulation activity of all fungi.
Polysaccharides, as well as their own, cause the apoptosis of breast cancer cells. Maitake extract amplifies the response of NK cells and increases the activity of macrophages and cytotoxic T cells. It inhibits the immunosuppression resulting from the action of certain chemotherapy agents, and thus reduces the hematological toxicity of certain chemotherapy agents.

There is an interesting action in diseases of the immune system.This fungus is also hypolipidemic, anti-atheromal and neuroprotective by supporting and regenerating the neural transmission network.

The most interesting components of Maitake appear to be polysaccharides, acting on the immune system.

Polypore versicolor (Coriolus versicolor-PSK):

Polypore is an anti-oxidant with anti-cancer properties. It would slow the spread of cancer cells and would therefore be antimetastatic.

“It is not the strongest of the species that survives, nor the smartest. He is the one who knows best how to adapt to change.” In this sentence, Darwin describes the nature of living organisms halfway between plants and animals that survived the great extinctions.