What is the equivalent of Extranase?

Extranase, a well-known name in phytotherapy, is frequently used for its anti-inflammatory and anti-oedematous properties. The active ingredient in Extranase is bromelain, an enzyme extracted from the stem of the pineapple plant, which plays a key role in the treatment of inflammation, especially in chronic or acute conditions such as sinusitis, post-operative oedema and muscle pain. Bromelain’s ability to help dissolve foreign proteins and stimulate the healing process makes it a therapeutic component of choice in a variety of medical treatments.

The aim of this article is twofold. Firstly, to highlight the merits of bromelain, taking a detailed look at its mechanisms of action, its therapeutic applications and the benefits demonstrated by various clinical studies. Secondly, we would like to introduce and discuss Stalyse, a product developed by the Prescription Nature laboratory, which is presented as an equivalent of Extranase with potentially improved formulations. This presentation will detail the composition, efficacy and specific benefits of Stalyse, positioning it as an innovative alternative in the landscape of bromelain-based treatments.

What are the benefits of Bromelain?

Bromelain is an enzyme complex found mainly in pineapple, especially in the stem and, to a lesser extent, in the fruit. This enzyme was first isolated in the 1800s and has since been widely studied for its many therapeutic applications. Unlike other proteolytic enzymes, bromelain has the unique ability to remain active in both the stomach and intestine, allowing a wide range of systemic actions once ingested.

How does bromelain work?

Bromelain’s mechanism of action is complex and multifactorial. Primarily, this enzyme works by hydrolysing proteins, enabling it to modulate various pathophysiological processes. In medicine, it is best known for its anti-inflammatory action. It inhibits the migration of neutrophils to sites of inflammation and reduces the production of pro-inflammatory cytokines, thereby facilitating a reduction in inflammation and oedema.

In addition, bromelain has an antithrombotic and anticoagulant action by interfering with several blood coagulation factors. It has also been shown to have fibrinolytic properties, helping to break down fibrin, a protein involved in the formation of blood clots. These actions make it useful not only for anti-inflammatory treatments, but also for managing conditions associated with poor circulation and increased risk of thrombosis.

What are the clinical properties of bromelain?

The clinical benefits of bromelain are well documented in the scientific literature. Its therapeutic applications include the treatment of sinusitis, muscle trauma,arthritis and post-operative oedema. Its effectiveness in reducing the symptoms of sinusitis, for example, has been compared with that of conventional drugs, offering a less aggressive alternative that is better tolerated by patients.

In addition, recent studies have explored the use of bromelain in the treatment of cancer, suggesting that its anti-inflammatory and immunomodulatory properties may play a role in reducing tumour growth and improving immune responses. However, these applications require further research for full validation.

Stalyse: The equivalent of Extranase

History and development

Stalyse represents a significant innovation in the field of food supplements, designed by the Prescription Nature laboratory. The product is the result of rigorous development aimed at maximising the benefits of bromelain, a natural proteolytic enzyme derived from pineapple. The formulation of Stalyse has been specially designed to offer a high concentration of active enzyme and ensure optimal assimilation thanks to its gastro-resistant capsules. This new formulation meets a growing need for effective natural solutions for pain management, digestion and drainage.

What is the composition of Stalyse?

Stalyse features an exceptional composition, centred on a high dose of natural bromelain, with 33,300 nKat per capsule, guaranteeing high potency for optimised therapeutic effects. The bromelain used in Stalyse is extracted from both the fruit and stem of the pineapple plant, areas rich in enzymes, and is titrated at 5,000 GDU/g, guaranteeing constant, effective enzymatic activity.

The capsules used for Stalyse are gastro-resistant DR caps®, designed to resist stomach acids. This allows the bromelain to be released and absorbed in the intestine, where it is most effective, increasing the product’s efficacy compared with less sophisticated formulations. This technology ensures that the bromelain remains intact and active, enhancing its therapeutic potential.

In addition, Stalyse is formulated without allergens, gluten, GMOs, excipients or nanoparticles, and is 100% vegan. It is also not tested on animals and is not irradiated, reflecting the laboratory’s commitment to responsible production that respects the environment and consumer health.

What is the pharmacokinetic profile of Stalyse?

The pharmacokinetic profile of Stalyse is marked by a number of distinctive features due to the product’s composition and galenic form. The DR caps® gastro-resistant capsules used for Stalyse play a crucial role in protecting bromelain from degradation by gastric acids. This protection ensures that the enzyme reaches the intestine, its optimal site of action, where it can be absorbed effectively.

Once in the intestine, bromelain is released and begins its proteolytic action, facilitating the digestion of food proteins. This targeted release contributes to a rapid onset of action, maximising the therapeutic efficacy of Stalyse. The enzyme also has a relatively high bioavailability, meaning that a large proportion of the dose administered becomes available to exert its biological effect in the body.

What to replace Extranase with?

The therapeutic benefits of Stalyse are numerous, reflecting the properties of the bromelain it contains. Stalyse has been proven to help :

• Improve digestion: By catalysing the breakdown of complex proteins, Stalyse aids digestion, reducing feelings of heaviness and postprandial gastric discomfort.
• Reduces inflammation: Bromelain has natural anti-inflammatory properties, effective in treating inflammatory conditions such as arthritis and other musculoskeletal inflammations.
• Promote elimination and drainage: By helping to break down proteins in the circulatory system, Stalyse can help to reduce oedema and promote lymphatic drainage.

In addition to these proven effects, the bromelain in Stalyse shows potential in other therapeutic applications, such as:

• Antithrombotic effect: Bromelain’s ability to interfere with clot formation may be beneficial in preventing thrombotic complications.
• Immune support: By modulating certain immune pathways, bromelain can help boost the body’s immune response.

Stalyse, with its highly concentrated formula and sophisticated delivery system, therefore represents a promising therapeutic option for those seeking health benefits through a natural and effective approach. The combination of its powerful enzymatic action and advanced formulation makes it a leading choice for treating a variety of conditions while supporting general wellbeing.

Advantages of Stalyse over Extranase

‘Which supplement can we replace Extranase with?’

In comparing Stalyse toExtranase, several aspects of their therapeutic efficacy are worth highlighting. Firstly, the concentration of bromelain is significantly different: Stalyse offers a high dose of 33,300 nKat per capsule, which is higher than many other products on the market, including Extranase. This high concentration ensures that Stalyse has a more powerful proteolytic capacity, which translates into greater efficiency in digesting proteins and reducing inflammation.

In addition, studies on bromelain indicate that its ability to reduce pain and inflammation and improve digestion is directly linked to the dose administered. With its highly concentrated formulation, Stalyse can therefore offer faster and more pronounced results in terms of symptom relief and recovery from injury or surgery.

Advantages of formulation and dosage

One of the key benefits of Stalyse is its advanced formulation using gastro-resistant capsules. This feature is essential as it allows bromelain to pass through the stomach without being degraded by stomach acids, a limitation common with other similar products such as Extranase. The protection offered by these gastro-resistant capsules ensures that the enzyme is released directly into the intestine, where it is most effective, maximising its absorption and biological action.

What’s more, Stalyse is formulated without allergens, gluten or GMOs. It is 100% vegan and contains no excipients or nanoparticles, offering a safer, healthier option for consumers concerned about their diet and overall health. These formulation details not only enhance the safety profile of Stalyse, but also contribute to its compatibility with a wide range of diets and personal preferences.