Andropause or age-related androgenic deficit (SAD) is defined as the set of physiological and psychological symptoms that may accompany the decline in androgen levels in aging humans. It would occur in particular around 45 years of age at age 65 and would appear less brutal than menopause in women.
What is andropause
Andropause doesn’t affect all men. Also, it does not mark the cessation of fertility. On the other hand, hormonal decline in humans is partial, progressive and inconsistent
In particular, andropause begins with a decrease in Leydigian secretion (testicular leydig cells), resulting in a decrease in free testosterone (increase in SHBG), a decrease in total testosterone. Consequence: elevation of gonadotrophins (LHRH).
Sensitivity to andropause is related to insulin metabolism, the complete endocrine axis (pituitary, hypothalamus, thyroid, adrenal) but also to the competence of the neurotransmitter system (serotonin, melatonin, dopamine, norepinephrine, adrenaline…)
The clinical expression of andropause
The onset of andropause is gradual and does not present a physical witness, unlike a woman whose physical witness to menopause is amenorrhea (the absence of menstruation).
However, the diagnosis of andropause, apart from a blood test, is evidenced by the addition of the following subjective symptoms: emotional instability, decreased muscle strength, decreased strength, decreased resistance to stress, decreased reaction rate, increased fat deposition around the stomach, sleep disorders, chronic pain, decreased libido, erectile dysfunction, decreased bone resistance and also general health consequences such as osteoporosis and a more vascular risk High.
These factors were associated with lower testosterone levels.
- Excessive use of alcohol and cannabis.
- Excess weight. A 4 or 5 point increase in body mass index would equate to a 10-year aging relative to the decrease in testosterone.
- Abdominal obesity. It corresponds to a waist circumference greater than 94 cm in humans.
- Diabetes and metabolic syndrome.
- Blood lipid levels, including cholesterol, outside normal levels.
- A chronic disease.
- Liver problems.
- Chronic stress.
- Taking certain medications, such as antipsychotics, certain antiepileptic drugs and narcotics
- A diversified lipid intake rich in essential fatty acids such as long chain polyunsaturated acids (arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid).
- Protein: The protein requirement is 1gr of protein per kilo of body weight.
- Micronutrients: the need for micronutrients: mineral richness (calcium, magnesium), selenium, zinc, live A, vit K, Vitamins of group B are important.
- A water intake of around 2 litres, of which a minimum of 0.7 litres is in the form of beverages, is essential.
- Avoid very sweet foods
- We must increase the consumption of nuts, hazelnuts, whole grains, legumes rich in magnesium, olive oil, soy, dried fruits, vegetables, fruits and limit animal fats.
Nutritional status is one of the essential factors in combating the rapid installation of andropause both in the quantity of intakes (36 kcal/kg) and on the quality characterized by:
Hygiene of life
Avoid oxidants such as tobacco and alcohol
The restoration of an ideal weight will allow a regulation of the 5 aromatase and the practice of moderate and regular physical exercise will have a favorable effect on both the psychic and physical parameters.
Biological balance of andropause
The blood dosage of testosterone and its derivatives is the most characteristic witness to an andropause.
- Testosterone: N – 4 to 9 g/l: the floor rate is 4 regardless of age
- Free testosterone: floor rate 1.3 g/L or even 0.7 but normality varies from laboratory to laboratory
However, these dosages are very sensitive and their interpretation is sometimes delicate
LH or LHRH
The blood test of gonadotrophins LHRH or LH can indeed determine the origin of hypo testosteroneemia:
- Hypo testosteremia – high LH sign a testicular impairment. Additional treatment may be considered
- Hypo testosteroneemia – normal or lowered LH may reflect a pathology of the hypothalamo-pituitary axis. A dosage of prolactin is necessary
Normal rate of LH – 1.7 to 7.7 g/l. In case of andropause the LH is around 5.6 to 13.6g/l
Other hormones such as growth hormone, DHEA (dihydroepiandrostenedione), melatonin… are in free fall
How to treat andropause
The treatment of andropause is primarily a hormonal treatment with testosterone. However, the side effects of hormonal treatment limit its use to patients with confirmed clinical and biological signs.
In case of contraindications to hormone therapy, the fight against the etiology of the problem and the use of symptomatic remedies will allow to pass over this difficult period.
In all cases, the treatment It must be supplemented by a preventive diet, an improvement of the detoxifications of the body and the addition of antioxidants
Hormone therapy: Testosterone
In intramuscular injections (about 1 per month, reimbursed by Social Security), tablets also reimbursed or gel (to be applied to the skin) not reimbursed. But other presentations orally or even in skin patch sticker (or patch) already marketed in the United States, should be released soon.
Warning: Treatment to consider after patient information on prostate cancer risk (30% of subjects at this age). This is why PSA dosage and rectal examination are essential before treatment.
Hormone therapy has a proven but not mandatory efficacy on bone densitometry and physical, psychological and sexual asthenia
Another hormonal treatment, based on chorionic gonadotrophins, is possible when testosterone levels are still normal but a little low. These stimulate the testicles to make more testosterone.
Treating andropause with dietary supplements
Androlistica® is a dietary supplement of andropause, consisting of specific fatty acids, phytosterols, OMEGA 3 sea fish, provitamins, minerals, and antioxidants
Its naturally occurring phytosterols, provitamins, minerals and antioxidants have all been studied to protect the body from premature aging. They contribute to the urinary balance and integrity of prostate cells.
The extracts of ootes and yam oppose the oxidation of phytosterols, contributing to the preservation of cell membranes, and contribute to the proper transformation of sterols into steroids whose main expression in humans is testosterone
Tips for use: 2 to 3 capsules per day during a meal, 3 weeks per month
How to improve andropause through homeopathy
Painful erection or ejaculation, Lack of libido; with nervous irritability, coitus back pain, reassembled, retracted
Sabal serrulata composed tablets, granules or drinkable solution: 3 granules 3/day or 10 drops 3/day
Remedy against andropause by herbal medicine
The use of plants that act as a precursor to essential hormones such as testosterone, melatonin and DHEA can also compensate for physiological decreases associated with andropause.
Plants to avoid
Be careful to avoid, however, oestrogenic plants such as Hops (Humulus lupulus), Sage (Salvia officinalis), or Ginseng (Panax Ginseng).
In any case
Glycine max (soy)
Its effects are manifold:
- Stability of bone density in both sexes after age 50.
- Introducing a cholesterol-lowering effect, a precursor to nitrogen monoxide (the most powerful vasodilator known)
- Slowing the rise of PSA in prostate cancer and prevention of prostate cancer.
- Kidney protection in diabetics and improved cognitive function (in a group capable of making equol from daedzine) in the presence of competent intestinal bacteria.
Land Tribe (Tribulus terrestris)
Specific plant also called The Maltese Cross which seems particularly interesting as it would raise testosterone levels
Rosmarinus, the Lycopene of the tomato, in association with the body’s detoxification plants likeChrysantellum americanum or other large polychrests like Carduus marianus.
- Pycnogenol extracted from grape seeds or pine bark is also a very powerful antioxidant of interest in the treatment of andropause
Depending on the disorder
Against emotional instability, decreased muscle power, decreased resistance to stress and decreased reaction speed, Eleuterococcus senticosus associated with magnesium will also improve the situation.
Tilia Tomentosa and Eleutherococcus senticosus
Decreased libido and erectile dysfunction will therefore be usefully compensated by the use of Sabal serrulata, selenium, zinc and VitB
Fighting andropause with gem therapy
Sequoia buds (Sequoia gigantea): Sequoia gigantea buds MG 1DH is indicated in case of adrenal insufficiency. It is an excellent anti-ageing wall man. It is also indicated in cases of osteoporosis.
Posology: Take 50 drops in a little water morning and evening before or after meals.
Pharmacy Tip: When to see a doctor?
Before any testosterone or DHEA treatment to check for risks and/or contraindications to treatment. In case of clinical signs of andropause in a young man
The blood dosage of testosterone and its derivatives is thus the most characteristic witness of an andropause.
The restoration of an ideal weight will ultimately allow a regulation of the 5 aromatase and the practice of moderate and regular physical exercise will have a favorable effect on both the psychic and physical parameters.